DMPQ: Write down the difference between antigen and antibodyand their role in vaccine development.


OverviewSubstance that can induce an immune responseProteins that recognize and bind to antigens
Molecule typeUsually proteins, may also be polysaccharides, lipids or nucleic acidsProteins
OriginWithin the body or externallyWithin the body


The Role of Antigens & Antibodies in Vaccinations

Vaccines contain antigens which stimulate the B lymphocytes of the immune system to respond by producing plasma cells which secrete disease specific antibodies (Primary response). Some of the B cells become memory B cells, which will recognise future exposure to the disease. This results in a faster and more intense production of antibodies, which effectively work to eliminate the disease by binding to the antigens (Secondary response).

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